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Genetics and Genomics

Genetics - Services

Advanced Genotyping: allows for a faster and more efficient multi-gene SNPs detection needed for the:

  • Detection of mutations and polymorphisms of genes associated with complex disorders.
  • Efficient follow-up of a therapy prescribed to evaluate the genetic markers that condition patient’s response.
  • Implementation of preventive medical protocols.
  • Study of pharmacogenomics : the influence of genetics over pharmaceutical drug metabolization, transport and receptor-mechanics helping to identify the response of patients to active ingredients.
  • For the study of nutrigenomics: the field of genomics that studies the influence of food over gene expression, protein synthesis and metabolism.
Applications:

1. Physicians and health professionals involved in the prediction and prevention and treatment of complex disorders.

2. Clinical trials

Gene Expression: is the process by which a gene's DNA sequence is converted into the functional or structural proteins of a cell.The amount of protein that a cell expresses depends on the tissue, the developmental stage of the organism and the metabolic or physiologic state of the cell. Gene expression is used for:

  • Determination of the expression pattern and quatification of the level of expression. This is done via the comparasion of a control sample with the sample under test. i.e. healthy tissues vs abnormal tissues.
  • Molecular caracterization of the accion of an active ingredient (pharmaceutical drugs or nutraceuticals) through the study of expression patterns in celular models or laboratory rats.
  • Screening and toxicology assessment of pharmaceutical drugs by the analysis of genetic expression variations during the drug administration period.
Applications:

Basic research of pharmaceutical or nutraceutical development.

Identification of GMOs & Microorganisms: allows for the detection of substances or organisms with different genetic structures needed for the:

  • Clinical diagnosis and detection of microorganims foreign to host’s cells. These can be tested both in food and living tissues to provide an accurate diagnosis of the genetic markers of the pathogen under study.
  • Identification of genetically modified organisms that do not comply with governmental regulations such as soya and maize
Applications:

- Food industry
- Regulatory Governmental institutions


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