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Genetics
and Genomics
Movement
Disorders
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Movement
Disorders are neurological conditions that affect speed, fluency,
quality, and ease of movement. Movement is produced and coordinated
by several interacting brain centres, including the motor cortex,
the cerebellum, and a group of structures in the inner portions
of the brain called the basal ganglia. Sensory information provides
a critical input which helps prevent opposing muscle groups from
contracting at the same time.
While the clinical appearance of this type of disorders range
from an inability |
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to
move, to severe constant and excessive movement, they are usually
divided into two groups; excessive movement (hyperkinetic movement
disorders) versus diminished movements (bradykinetic movement
disorders). Movement disorders tend to be chronic and progressively
disabling. However, latest advances in genetics, drug development
and surgical techniques have encouraged novel diagnosis and treatments.
Movement Disorder Genetics
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